
COVID-19
Clear, up-to-date information on COVID-19 to help protect you and your loved ones.
About COVID-19
COVID-19 is a disease caused by a new form of coronavirus, first reported in December 2019. Coronaviruses are a large family of viruses that cause respiratory infections. These can range from the common cold to more serious diseases.
Variants
Covid-19 viruses can mutate (change) themselves when they replicate (make copies of themselves). Viruses that have mutated in this way are called variants.
There have been many identified SARS-CoV-2 virus variants as the virus mutates and evolves over time. Omicron, a variant of the SARS-CoV-2 virus, was first identified in November 2021 and was officially designated as a variant of concern by the World Health Organization (WHO) shortly thereafter.
Each variant and subvariant is associated with varying levels of transmissibility, immune escape, and disease severity.
What’s important is for people to stay vigilant, ensure they are vaccinated against the virus (particularly for at-risk individuals with underlying medical conditions), and continue to apply non-pharmaceutical practices during outbreaks.

COVID-19 Symptoms
Symptoms of COVID-19 can range from mild illness to pneumonia. Some people may get very sick very quickly, and most people will recover easily. People with coronavirus may experience symptoms such as:1
- Fever
- Coughing
- Sore throat
- Shortness of breath
Other symptoms can include runny nose, acute blocked nose (congestion), headache, muscle or joint pains, nausea, diarrhoea, vomiting, loss of sense of smell, altered sense of taste, loss of appetite and lethargy.2
If you are concerned that you, or anyone close to you may have COVID-19 symptoms, you can use the HealthDirect COVID- 19 Symptom and Antiviral Eligibility Checker.


How COVID-19 Spreads
The virus can spread from person to person through:
- close contact with an infectious person (including in the 48 hours before they had symptoms)
- contact with droplets from an infected person’s cough or sneeze
- touching objects or surfaces (like doorknobs or tables) that have droplets from an infected person, and then touching your mouth or face.
Current evidence suggests that the most likely spread is from respiratory droplets between people from close contact with each other.3, 4
People are believed to be most infectious two days before they start showing symptoms.5 However even if people do not show any symptoms, they can still spread the virus to other people.

COVID-19 Complications
Most people will recover from Covid-19 within a few weeks, however it can cause serious complications. Older people and those with underlying medical conditions e.g. heart disease, diabetes, obesity, chronic liver disease, severe asthma and cystic fibrosis may be more likely to develop a more serious illness.6
What causes Covid-19 complications?
Covid-19 complications may be caused by a cytokine storm. Cytokines are inflammatory proteins that can flood the bloodstream after an infection like COVID-19 triggers the immune system. The large influx of cytokines can cause damage to many organs of the body like the heart, lungs, liver and kidneys.7
The most common complications are of the lungs and respiratory system, they are:
- Pneumonia: an infection that affects one or both lungs. The air sacs in the lungs become inflamed making it harder to breathe. This type of pneumonia may cause scar tissue and long-term damage to the lungs.7
- Acute Respiratory Distress Syndrome: the lungs become so severely damaged that fluid flows into them which inhibits the body getting oxygen into the bloodstream.7
The other complications may be:
- Acute liver injury: when the liver suddenly stops working8
- Acute cardiac injury: damage to the heart8
- Secondary infection: when the body develops another infection unrelated to Covid-19 e.g., a bacterial infection like Strep or Staph9
- Acute kidney injury: an abrupt decrease in kidney function10
- Septic shock: a life-threatening condition when the blood pressure drops to a dangerously low level after an infection11
- Disseminated intravascular coagulation: the body doesn’t clot properly, forming abnormal clots which can lead to internal bleeding and organ failure12
- Blood clots: clumping of blood cells in the blood vessels13
- Multisystem inflammatory syndrome in children: some organs in the body become severely inflamed. Symptoms include fever, belly pain, vomiting, diarrhoea, headache, rash and confusion14
- Chronic fatigue: Symptoms may include brain fog, severe fatigue, pain, trouble thinking or dizziness15
- Rhabdomyolysis: muscles break down and tissues die. As the cells break, a protein is released into the bloodstream which if the kidneys can’t clear, it could be fatal16
- Damage to the brain: even in young people, COVID-19 can cause strokes and Guillain Barre Syndrome.17,18
People with severe symptoms may be hospitalised and treated in the Intensive Care Unit with mechanical devices such as ventilators. Surviving these experiences can make them more likely to suffer from post-traumatic stress disorder, depression and anxiety.19,20,21
Long COVID
WHO defines Long COVID as the continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection with these symptoms lasting for at least 2 months with no other explanation.22
The symptoms may include fatigue, shortness of breath and cognitive dysfunction.
10–20% of people with over 17 million people across the WHO European Region have experienced Long Covid during the first two years of the pandemic (2020/21).22
In Australia, an AIHW review found that 5–10% of COVID-19 cases reported symptoms persisting for more than 3 months with the vast majority resolving within 12 months.23
The key risk factors include: severe COVID-19 illness, comorbidities, female, mid-adult age groups23
Two COVID-19 vaccination doses are associated with a 13% to 47% lower risk of symptoms persisting beyond 4 weeks.24
The Immunisation Coalition has supported the development of the CoRiCal Long-COVID Calculator which provides a personalised risk assessment of developing long COVID 6 months after infection.
Who is Most at Risk?
You are at a high risk of becoming very sick from COVID-19 and needing hospital treatment, if you25:
- are aged 65 years or older
- have certain health conditions, including
- weakened immune system
- neurological disease, such as stroke or dementia
- chronic lung disease, such as severe asthma or chronic obstructive pulmonary disease
- heart disease
- obesity
- diabetes
- chronic kidney disease
- are pregnant.
High risk settings include25:
- residential aged care facilities
- disability care services
- in-home aged, health and disability care
- hospitals and other healthcare settings.
Among patients with vaccine breakthrough COVID-19 hospitalisations, 40-44% had immunosuppression.26,27

COVID-19 Prevention
There are several things you can do to prevent the spread of COVID-19, such as;
- Practise good hygiene: wash your hands, keep home and workplaces clean and covering your mouth when you cough.
- Masks: wear a mask when you are sick. Make sure the mask covers your nose and your mouth.
- Isolate: if you have contracted COVID-19 it is strongly recommended that you stay at home. Although it is no longer a legal requirement to isolate, staying at home protects the people around you and the general community from COVID-19. You should avoid entering high risk settings like aged and disability care facilities and hospitals unless seeking immediate medical care. At home, keep the room well ventilated. Monitor yourself for any symptoms and call your health care provider if you have difficulty breathing, loss of speech or mobility, confusion or chest pain. Stay positive, contact family and friends regularly, maintain regular exercise at home and monitor your mental health. The isolation period is 5-7 days or when symptoms have resolved, whichever is the longer period.
COVID-19 Vaccination
Infants, children and adolescents
Healthy infants, children and adolescents aged <18 years are not recommended to receive COVID-19 vaccine
Adults
Adults aged ≥18 years are recommended to receive COVID-19 vaccine, and further doses are recommended based on age and risk-benefit assessment
People with medical conditions that increase their risk of severe illness
People with medical conditions that increase their risk of severe illness from COVID-19 are recommended to receive further doses of COVID-19 vaccine
Women who are pregnant or breastfeeding
Unvaccinated pregnant women are recommended to receive COVID-19 vaccine
Vaccinated pregnant women are not recommended to receive further doses of COVID-19 vaccine during pregnancy
People with a history of SARS-CoV-2 infection
People with a history of SARS-CoV-2 infection can receive further doses of COVID-19 vaccine as recommended
accinated are not routinely recommended to have a further dose of COVID-19 vaccine. However, they can consider a further dose of COVID-19 vaccine based on presence of underlying risk conditions and/or personal preference35].

COVID-19 Treatment
Doctors will need to review patients’ medications and their current medical conditions to decide if a COVID-19 treatment is suitable for them. The types of COVID-19 treatments that are suitable will also depend on the severity of their COVID-19 illness.
Basic in hospital treatment options include: oxygen for severely ill patients, ventilation for patients who are critically ill and the use of Dexamethasone or other corticosteroids. Antivirals, immune modulators and monoclonal antibodies have also been used.
Severity of COVID-19
Mild Illness: Individuals who have any of the various signs and symptoms of COVID-19 (e.g., fever, cough, sore throat, feeling unwell, headache, muscle pain, nausea, vomiting, diarrhea, loss of taste and smell) but who do not have shortness of breath, difficulty breathing or abnormal chest imaging. These individuals do not require oxygen.32
Moderate Illness: Individuals who show evidence of lower respiratory disease (e.g. pneumonia) during clinical assessment or imaging and who have low oxygen levels. These individuals require oxygen. 32
Severe Illness: Individuals who have lower respiratory disease with severely low levels of oxygen in their blood. These individuals require oxygen. 32
Critical Illness: Individuals who have respiratory failure (where the lungs have trouble loading oxygen or removing carbon dioxide), septic shock (blood pressure drops to a dangerously low level after an infection), and/or multiple organ dysfunction. These individuals require oxygen. 32
Natural Treatments
Natural treatments such as zinc, melatonin, vitamin C, vitamin D, and other supplements are readily available and commonly used to help prevent or treat COVID-19; however, there is insufficient data to recommend the use of such for the prevention or treatment of COVID-19.
The Immunisation Coalition takes an evidence-based approach to COVID-19 treatment.

More COVID-19 Information
Australian Department of Health: Coronavirus (COVID-19) resources for the general public
ACT Government: COVID-19
Department of Health and Human Services Victoria: Coronavirus (COVID-19)
Coronavirus Victoria: Translated information about COVID-19
Coronavirus Victoria: Symptoms and Risks
Coronavirus Victoria: Education – Information for parents, students and educators
NSW Health: COVID-19 Frequently Asked Questions
Northern Territory Department of Health: Coronavirus
Western Australia: COVID-19 (Coronavirus)
Queensland Health: Coronavirus(COVID-19)
References
- Australian Government Department of Health and Aged Care. COVID-19: Women who are pregnant or breastfeeding [Internet]. Australian Immunisation Handbook. Canberra: Department of Health and Aged Care; [cited 2025 Jul 17]. Available from: https://immunisationhandbook.health.gov.au/contents/vaccine-preventable-diseases/covid-19#women-who-are-pregnant-or-breastfeeding
- About COVID-19 [Internet]. health.gov.au. [cited 2024 Aug 27]. Available from: https://www.health.gov.au/topics/covid-19/about
- COVID-19 symptoms [Internet]. healthdirect.gov.au. [cited 2024 Aug 27]. Available from: https://www.healthdirect.gov.au/covid-19/symptoms#:~:text=mild%20upper%20respiratory%20tract%20symptoms,mild%20headache
- World Health Organization. Coronavirus disease (COVID-19): How is it transmitted? Accessed 19 October 2022
- Brooks JT, Butler JC. Effectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2. JAMA. 2021;325(10):998–999. doi:10.1001/jama.2021.1505
- Information for people who test positive for COVID-19 [Internet]. covid19.act.gov.au. [cited 2024 Aug 27]. Available from: https://www.covid19.act.gov.au/stay-safe-and-healthy/information-for-people-who-test-positive-for-covid-19
- Table: Conditions for which COVID-19 vaccination can be considered [Internet]. immunisationhandbook.health.gov.au. [cited 2024 Aug 27]. Available from: https://immunisationhandbook.health.gov.au/resources/tables/table-conditions-for-which-covid-19-vaccination-can-be-considered
- Tazarghi A, Bazoq S, Taziki Balajelini MH, et al. Liver injury in COVID-19: an insight into pathobiology and roles of risk factors. Virol J. 2024;21:65. https://doi.org/10.1186/s12985-024-02332-y
- Qiu H, Li J, Li J, Li H, Xin Y. COVID-19 and Acute Cardiac Injury: Clinical Manifestations, Biomarkers, Mechanisms, Diagnosis, and Treatment. Curr Cardiol Rep. 2023 Aug;25(8):817-829. doi: 10.1007/s11886-023-01902-w. Epub 2023 Jun 14. PMID: 37314650.
- Jeong H, Malik A, Boricha A, et al. Assessment of blood markers to predict risk of stroke in middle-aged to elderly population using machine learning. Sci Rep. 2021;11(1):13422. doi:10.1038/s41598-021-92220-0.
- Aklilu AM, Kumar S, Nugent J, et al. COVID-19−Associated Acute Kidney Injury and Longitudinal Kidney Outcomes. JAMA Intern Med. 2024;184(4):414–423. doi:10.1001/jamainternmed.2023.8225
- Cidade JP, Coelho LM, Costa V, et al. Septic shock 3.0 criteria application in severe COVID-19 patients: An unattended sepsis population with high mortality risk. World J Crit Care Med. 2022 Jul 9;11(4):246-254. doi: 10.5492/wjccm.v11.i4.246. PMID: 36051940; PMCID: PMC9305684
- Gando S, Akiyama T. Disseminated intravascular coagulation is associated with poor prognosis in patients with COVID-19. Sci Rep. 2024;14:12443. https://doi.org/10.1038/s41598-024-63078-9.
- Martin AI, Rao G. COVID-19: A Potential Risk Factor for Acute Pulmonary Embolism. Methodist Debakey Cardiovasc J. 2020 Apr-Jun;16(2):155-157. doi: 10.14797/mdcj-16-2-155. PMID: 32670476; PMCID: PMC7350811.
- Multisystem Inflammatory Syndrome in Children (MIS-C) – Symptoms and Causes [Internet]. mayoclinic.org. [cited 2024 Aug 27]. Available from: https://www.mayoclinic.org/diseases-conditions/mis-c-in-kids-covid-19/symptoms-causes/syc-20502550#:~:text=But%20in%20children%20with%20MIS,have%20had%20a%20known%20infection.
- Vu QM, Fitzpatrick AL, Cope JR, Bertolli J, Sotoodehnia N, West T, et al. Estimates of Incidence and Predictors of Fatiguing Illness after SARS-CoV-2 Infection. Emerg Infect Dis. 2024;30(3):539-547. https://doi.org/10.3201/eid3003.231194
- Rhabdomyolysis is a life-threatening complication in patients with COVID-19 [Internet]. ijidonline.com. [cited 2024 Aug 27]. Available from: https://www.ijidonline.com/article/S1201-9712(23)00713-0/fulltext#:~:text=Rhabdomyolysis%20is%20a%20life%2Dthreatening,in%20patients%20with%20COVID%2D19
- COVID-19 related stroke in young individuals [Internet]. thelancet.com. [cited 2024 Aug 27]. Available from: https://www.thelancet.com/article/S1474-4422(20)30272-6/fulltext
- Association Between Guillain-Barré Syndrome and COVID-19 Infection and Vaccination [Internet]. neurology.org. [cited 2024 Aug 27]. Available from: https://www.neurology.org/doi/10.1212/WNL.0000000000207900
- Post-COVID conditions: Information for healthcare providers. Centers for Disease Control and Prevention. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/post-covid-conditions.html. Accessed 19 October 2022
- Post-COVID-19 conditions. Centers for Disease Control and Prevention.
- COVID-19 (coronavirus): Long-term effects, Mayo Clinic, https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-long-term-effects/art-20490351. Accessed 19 October 2022
- WHO Post COVID 19 condition (Long Covid) Fact sheet Accessed 26 April 2023
- Australian Government Australian Institute of Health and Welfare Long COVID in Australia- a review of the literature Last updated 16 December 2022
- Brosh-Nissimov T et al. Clin Microbiol Infect. 2021;27:1652–1657
- Australian Government Department of Health and Aged Care. High risk groups and settings [Internet]. Canberra: Department of Health and Aged Care; [cited 2025 Jul 17]. Available from: https://www.health.gov.au/topics/covid-19/high-risk-groups-and-settings
- Tenforde MW et al. Clin Infect Dis. 2021;ciab687
- Australian Government Department of Health Protect yourself and others from COVID 19 Last updated 14 October 2022
- 32. ATAGI statement on the administration of COVID-19 vaccines in 2025 [Internet]. health.gov.au. [cited 2025 July 17]. Available from https://www.health.gov.au/resources/publications/atagi-statement-on-the-administration-of-covid-19-vaccines-in-2025?language=en
- Oral treatments for COVID-19 [Internet]. health.gov.au. [cited 2024 Aug 27]. Available from: https://www.health.gov.au/topics/covid-19/oral-treatments
- Paxlovid® (nirmatrelvir and ritonavir) Product Information [Internet]. tga.gov.au. [cited 2024 Aug 27]. Available from: https://www.tga.gov.au/sites/default/files/paxlovid-pi.pdf
- Lagevrio® (molnupiravir) Product Information [Internet]. tga.gov.au. [cited 2024 Aug 27]. Available from: https://www.tga.gov.au/sites/default/files/lagevrio-pi.pdf
- BMJ Best Practice. COVID-19: assessment of severity [Internet]. London (GB): BMJ Publishing Group; 2024 [cited 2024 Nov 22]. Available from: https://bestpractice.bmj.com/topics/en-gb/3000201/criteria?
- Victorian Department of Health. Vaccines and medications in patients with COVID-19 [Internet]. Melbourne: State Government of Victoria; [cited 2025 Jul 17]. Available from: https://www.health.vic.gov.au/covid-19/vaccines-and-medications-in-patients-with-covid-19
- Therapeutic Goods Administration (TGA). Veklury (remdesivir) – Australian Product Information [Internet]. Canberra: Australian Government Department of Health and Aged Care; [cited 2025 Jul 17]. Available from: https://www.tga.gov.au/resources/auspmd/veklury